Program Scope:
Five-lecture series on developmental biology, featuring one hour of lecture, one hour of directed laboratory exercise to aid in transferring into use in the high school curriculum.

Program Schedule:
Wednesday afternoon/evenings:
Lecture 4:00 – 5:00 p.m
Laboratory 5:00 – 6:00 p.m.
Dinner (will be provided) 6:00 – 7:00 p.m.

Cost: The program is FREE; enrollment is limited to 30 participants; register ASAP

Application Requirements:
Applicants must be full-time teachers or curriculum directors in a public, private, parochial, or charter school in Massachusetts, Rhode Island, or New Hampshire.

Application Deadline: September 21, 2002
Applicants will be notified of participation by October 1, 2002, and a packet of materials will be sent containing directions, maps, and parking permits.

Parking:
Because of the lack of parking spaces in the Harvard Square area, parking permits will be provided to participants to allow access to a nearby Harvard parking lot. A parking space is not guaranteed; however late in the afternoon spaces are likely to be available. Participants may also park at the Alewife garage on the Red Line and take the T to Harvard Square.

Resource Materials: Materials to be given to each participant will include papers selected by the lecturers, laboratory protocols and work-sheets, and other pertinent materials to facilitate transfer of the information and adaptation of the laboratory techniques to the typical high school lab.

10 Professional Development Points will be awarded to those who attend all five lectures.

Wednesday, October 9
Dr. Douglas Melton, Thomas Dudley Cabot Professor in the Natural Sciences

Dr. Melton will discuss embryonic and adult stem cells and their potential therapeutic uses. In addition, he will describe the cloning of animals and the scientific questions that can be addressed by cloning. Both cloning and stem cells will be discussed within their historical, moral and political contexts.

Wednesday, October 23
Dr. Elizabeth Robertson, Professor of Molecular and Cellular Biology

The ability to manipulate the genome of the laboratory mouse provides a powerful approach to understanding how individual genes function in the context of the normal animal. The lecture will focus on the various techniques that have been developed for engineering the mouse genome and how they can be used to explore the genetic pathways controlling development and disease.

Wednesday, November 6
Dr. Craig Hunter, Associate Professor of Molecular and Cellular Biology

RNA Interference (RNAi) is a recently discovered and exciting means of gene regulation in plants and animals. Double-stranded RNA homologous to a target gene is introduced into a cell and silences the target gene. Remarkably, this RNAi signal is transmitted between cells in plants and nematodes. Dr. Hunter will discuss how RNAi is being used to investigate gene function in a variety of organisms, and his search for the way in which the RNAi signal is communicated from cell to cell.

Wednesday, November 20
Dr. Andrew McMahon, Frank B. Baird, Jr., Profess of Science, and Chair, MCB

During embryonic life, the foundation of the adult body plan is established. How do the cells of different tissues form, and what determines where these cells are located and how numerous they are? Dr. McMahon will discuss the role of organizing centers within the embryo that use intercellular signaling to coordinate the long-range mammalian body plan.

Wednesday, December 4
Dr. Clifford J. Tabin, Professor of Genetics, Harvard-MIT Faculty of Health Sciences and Technology

To us, the human body’s left side appears to mirror the right side; however, internally, human anatomy is far from symmetric. All humans have hearts on their left sides, but how does this predictable asymmetry develop from a symmetric embryo? Dr. Tabin will describe recent work with chick and mouse embryos that illuminates how basic internal organization is specified.

For Additional Information:
For more information on this and other outreach programs offered by MCB, please contact Tara Bennett, MCB-HHMI Outreach Coordinator. (617) 496-3457.

To apply, paste the below text into an email and fill out the blanks. Please send the email to Tara Bennett by September 21st.

Name ______________________________

Home Address ____________________________________

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School Name ________________________

School Address ___________________________________

City State Zip ________________________

School phone: _______________________

Email ______________________________

o Public o Private o Charter o Parochial

Size of School: _____________________

Teaching responsibilities: ___________________________

Teaching at What Grade Level: __________

Have you attended MCB Teacher Programs in the past? If so what and when?

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