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Postdoctoral Fellow

Houqing Yu

Postdoctoral Fellow

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Research

The abundance of all the proteins in a cell’s proteome defines the structural and functional state of the cell. The steady-state levels of many proteins are under dynamic and delicate equilibrium between synthesis and destruction. In eukaryotic cells, two pathways largely control the removal of many damaged or unneeded proteins: the ubiquitin-proteasome system and the autophagy pathway. After working on the recognition between the proteasome and its substrates during my PhD, I joined the Denic lab and focused on the regulatory mechanism of the peroxisome autophagy (pexophagy) in budding yeast.