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Tag: Joshua Sanes

A ROLE FOR MICRORNAS IN AMYOTROPHIC LATERAL SCLEROSIS

(L to right) Gregorio Valdez and Joshua R. Sanes The great baseball player, Lou Gehrig, gave his name to the neurodegenerative disease that killed him, Amyotrophic Lateral Sclerosis.…

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WHAT’S “UP” WITH MOUSE VISION?

Co-authors (L to R) Yifeng Zhang, Markus Meister, Joshua R. Sanes, In-Jung Kim, and Masahito Yamagata, A mouse is small, close to the ground. Hawks and cats may…

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TECHNICOLOR BRAINS: MAPPING NEURAL CIRCUITS IN “BRAINBOW” MICE

The co-authors (left to right): Ju Lu, Jeff W. Lichtman, Jean Livet, Joshua R. Sanes, Tamily A. Weissman, Ryan W. Draft, Hyuno Kang More than a century ago,…

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A KINASE PATHWAY REQUIRED FOR NEURONAL POLARITY

Authors Josh Sanes (left) and Brendan Lilley Directional flow of information within the nervous system depends upon the ability of neurons to divide themselves into discrete compartments. Most…

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TARGET-DERIVED SIGNALS ORGANIZE MOTOR NERVE TERMINALS

Authors Michael Fox (left) and Josh Sanes The synapse is the heart of the nervous system, the site at which information is processed and passed between cells. Proper…

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A NEW WAY TO STUDY SPINAL CORD INJURY

First-author Florence Bareyre A tragic truth is that the mammalian central nervous system (CNS) has very limited ability to regenerate following injury. There is intense interest in trying…

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MAMMALIAN SAD KINASES ARE REQUIRED FOR NEURONAL POLARIZATION

A recent study by Kishi et al. shows how research programs can take unexpected directions. The authors wanted to study how small parts of neuronal processes become specialized…

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