Harvard University - Department of Molecular & Cellular Biology


Source: Kunes Lab

Gallery Image

"A laser scanning confocal micrograph of an approximately 15 micron field in the brain of Drosophila. The region shown is the "calyx of the mushroom body", a region of interest because its synapses have been implicated in memory storage. The image shows these synapses in red and green. Each of the round or oval fluorescent shapes is a synaptic site, specifically a "pre-synaptic bouton". The red fluorescence is the protein choline acetyltransferase, which synthesizes the neurotransmitter acetylcholine in the pre-synaptic zone of the axon terminal. The green fluorescence is the fluorescent protein EYFP, which is localized to the same pre-synaptic zones.

The mechanism of this localization relates to our current publication, because it is due to 3'UTR sequences on the mRNA from which it is synthesized. The mRNA is localized to the synapses, and translated into protein there."

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updated: 05/05/2015