Harvard University - Department of Molecular & Cellular Biology

DETECTING BIOPOLYMER CHARACTERISTICS IN A NANOPORE

Source: Branton Lab

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"Solid state nanopores are fabricated by closing 100 nm diameter pores down to single digit nanometer dimensions using ion-beam sculpting. When a polymer, such as DNA, is drawn through such a nanopore, the electrical properties of the nanopore are altered in a manner that reflect the DNA length, the way it is folded on itself, and other structural features. Eventually, we hope to develop nanopores into sensing elements that can provide high speed DNA sequence information."

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updated: 04/22/2014