News from 2015

  • Research

ESTABLISHING CELL FATE WITH A POLE-VAULTING PHOSPHATASE [LOSICK LAB]

Niels Bradshaw (l) and Rich Losick An important question in biology is how genetically identical cells activate different sets of genes. This is particularly perplexing for cells that…

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  • Research

“PERSONALIZED LESSON” MAY NOT BE DOPAMINE’S WAY [UCHIDA LAB]

(l to r) Nao Uchida, Sachie K Ogawa, William Menegas, Mitsuko Watabe-Uchida and Yoh Isogai Dopamine, originally referred to as a pleasure molecule, is now one of the…

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  • Archive

THE ELEGANCE OF DENDRITES AND WHY IT MATTERS [SANES LAB]

Joshua Sanes (l) and Dimitar Kostadinov The dendritic processes of neurons form elaborate branched arbors that are stereotyped among neurons of a specific type but differ markedly among…

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  • Archive

RADIO BROADCASTING IN CELLS [O’SHEA LAB]

Anders Sejr Hansen To survive, cells must monitor their environments and elicit appropriate and timely responses to external stresses such as nutrient deprivation. In general, cells achieve this…

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  • Archive

HARNESSING THE POWER OF AMAZON’S CLOUD IN A NEW ERA FOR STRUCTURAL BIOLOGY [LESCHZINER LAB]

(l) Andres Leschziner and Michael Cianfrocco Structural biology is currently undergoing a revolution: single-particle cryo-electron microscopy (cryo-EM) has recently realized its potential for routinely determining the structures of…

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  • Archive

THE WHERE AND WHY OF GENE EXPRESSION [SCHIER LAB]

(l to r) Jeff Farrell, Alex Schier, and Julien Dubrulle While most cells in the body have the same DNA, and thus the same set of genes, cells…

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  • Archive

FEELING GOOD OR BAD LATELY? LISTEN TO SEROTONIN [UCHIDA LAB]

(l to r) Mackenzie Amoroso, Jeremiah Cohen, and Nao Uchida Serotonin is one of the most widespread and mysterious neurotransmitters in the brain. It has been proposed to…

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  • Archive

LIS1 [LESCHZINER LAB]

(l to r) Kat Toropova, Andres Leschziner,Sam Reck-Peterson, Sirui Zou and  (front row) Locksley Cytoskeletal motors are molecular machines that “walk” along the filaments that provide structural support…

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  • Archive

STOCHASTIC ORGANELLE BIOGENESIS [O’SHEA LAB]

Erin O’Shea and Shankar Mukherji Cells are kind of like little people. Just like we have organs like our heart, lungs and brain that are responsible for core…

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  • Archive

SEXUALLY DIMORPHIC MAMMALIAN BRAIN FUNCTION AT THE SINGLE NEURON LEVEL [DULAC LAB]

Catherine Dulac and Joe Bergan An animal's survival depends critically on its ability to identify friends and foes in its environment and respond to each with suitable behaviors.…

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