News from 2019

A Closer Look at Neuronal Rewiring in Brain Development [Lichtman Lab]

In many vertebrates, neural circuits undergo substantial reorganization in early postnatal life. This reorganization strengthens some neuron-to-neuron connections, while other neuronal connections are weakened by synapse elimination. It…

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Paint Colors on a Connectomic Map [Lichtman Lab]

[caption]Tao Fang (l) and Hidde Ploegh[/caption] Brain is arguably the most complicated biological tissue. Many different cell types are intertwined and interconnected. Moreover the number of different cell…

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Harvard Researchers Among Those Receiving More Than $150 Million in Funding from the NIH BRAIN Initiative

Harvard scientists are among dozens of researchers who will receive more than $150 million in funding over the next five years through the National Institute of Health’s Brain…

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The First Nanoscale Rendering of an Entire Vertebrate Brain

People frequently operate computer devices such as smartphones that collect user input and process this information to produce outputs on a display or through headphones.  Engineers control how…

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IN-THE-NEWS; INTERVIEW WITH JEFF LICHTMAN

The journal Neuron conducted a Q&A (PDF) with Jeff Lichtman. View Jeff Lichtman's Faculty Profile  

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RECONSTRUCTION OF GENETICALLY IDENTIFIED NEURONS IMAGED BY SERIAL-SECTION ELECTRON MICROSCOPY [SANES AND LICHTMAN LABS]

Neurons connect with each other to form complex circuits that underlie mental activities. Mapping these connections to obtain a so-called wiring diagram is an essential step in learning…

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VISUALIZING SYNAPTIC NETWORKS IN THE VISUAL THALAMUS [LICHTMAN LAB]

In vertebrate nervous systems, vast interconnected networks of neurons underlie brain function.  Connectomics is a new field that attempts to map out these networks.  At the forefront of…

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RECONSTRUCTING THE BRAINS WIRING DIAGRAM [LICHTMAN LAB]

(l to r) Jeff Lichtman, Josh Morgan, Jose Conchello, Daniel Berger, and Richard Schalek This paper describes a suite of automated technologies designed to probe the structure of…

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CLEARED TISSUE IMAGING AT THE HARVARD CENTER FOR BIOLOGICAL IMAGING

Jeff Lichtman (l) and Doug Richardson The Harvard Center for Biological Imaging (HCBI) recently celebrated its five year anniversary. A central pillar in its mandate is to ensure…

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