News from 2019

A Small but Important Difference [Sanes Lab]

Neurons come in a bewildering variety of shapes and sizes, with the structure of each type underlying its specific functions. A major preoccupation of developmental biologists is to…

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Weathering the Storm of Axonal Injury [Sanes Lab]

Injury to the central nervous system (brain or spinal cord) usually leads to irreversible loss of function. This is because many injured neurons die and few if any…

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Joshua Sanes Receives Cowan Award for Research on Neural Development

MCB faculty Joshua Sanes is the 2019 recipient of the W. Maxwell Cowan Award for achievement in the study of neural development. The biennial award was established in…

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MCB Professor Wins grant to Map the Eye

Joshua Sanes, the Jeff C. Tarr Professor of Molecular and Cellular Biology and the Paul J. Finnegan Family Director for Harvard’s Center for Brain Science, will head a…

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What We See with When We Look Straight Ahead [Sanes Lab]

As a particularly accessible part of the central nervous system, the mouse retina has emerged as a favorite model for analyzing the development, structure and function of neural…

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A Family Affair [Sanes Lab]

Each part of the mammalian brain holds a large number of neuronal types – at least a hundred and perhaps a thousand or more.  These cells connect up…

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Putting Dendrites in the Right Place [Sanes Lab]

Dendrites are the antennae of neurons, receiving synaptic signals from other neurons. A critical aspect of wiring up complex neural circuits is to make sure that dendrites are…

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Scaling Up the Search for Neuronal Wiring Molecules [Sanes Lab]

Neural circuits in the mammalian brain comprise hundreds to millions of neurons, connected with each other in complex and highly specific ways. Studies over the past few decades…

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Turning the ON off: Sculpting One of Two Dendritic Branches in a Retinal Neuron [Sanes Lab]

The dendritic arbors of neurons are incredibly diverse in size and shape.  This makes sense, because dendritic morphology is a critical determinant of the numbers and types of…

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MCB Professor Wins Top Neuroscience Award

MCB professor Joshua Sanes has won this year’s Gruber Neuroscience Prize; a valuable international award given by the Society for Neuroscience and funded by Yale University’s Gruber Foundation.…

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