News from 2019

  • Research

MCB Professor Wins grant to Map the Eye

Joshua Sanes, the Jeff C. Tarr Professor of Molecular and Cellular Biology and the Paul J. Finnegan Family Director for Harvard’s Center for Brain Science, will head a…

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  • Research

What We See with When We Look Straight Ahead [Sanes Lab]

As a particularly accessible part of the central nervous system, the mouse retina has emerged as a favorite model for analyzing the development, structure and function of neural…

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  • Research

A Family Affair [Sanes Lab]

Each part of the mammalian brain holds a large number of neuronal types – at least a hundred and perhaps a thousand or more.  These cells connect up…

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  • Research

Putting Dendrites in the Right Place [Sanes Lab]

Dendrites are the antennae of neurons, receiving synaptic signals from other neurons. A critical aspect of wiring up complex neural circuits is to make sure that dendrites are…

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  • Research

Scaling Up the Search for Neuronal Wiring Molecules [Sanes Lab]

Neural circuits in the mammalian brain comprise hundreds to millions of neurons, connected with each other in complex and highly specific ways. Studies over the past few decades…

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  • Research

Turning the ON off: Sculpting One of Two Dendritic Branches in a Retinal Neuron [Sanes Lab]

The dendritic arbors of neurons are incredibly diverse in size and shape.  This makes sense, because dendritic morphology is a critical determinant of the numbers and types of…

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  • Research

MCB Professor Wins Top Neuroscience Award

MCB professor Joshua Sanes has won this year’s Gruber Neuroscience Prize; a valuable international award given by the Society for Neuroscience and funded by Yale University’s Gruber Foundation.…

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  • Research

MOLECULAR COMPETITION ENHANCES SYNAPTIC SPECIFICITY [SANES LAB]

As neurons develop in the central nervous system, they encounter many potential synaptic partners, and choose among them to form stable connections with only a few. The specific…

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  • Research

STAMP COLLECTING GETS IMPORTANT [SANES LAB]

The complex circuits of the brain are built from thousands of types of neurons. More than a century ago, Santiago Ramon y Cajal founded what we now call…

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  • Research

RECONSTRUCTION OF GENETICALLY IDENTIFIED NEURONS IMAGED BY SERIAL-SECTION ELECTRON MICROSCOPY [SANES AND LICHTMAN LABS]

Neurons connect with each other to form complex circuits that underlie mental activities. Mapping these connections to obtain a so-called wiring diagram is an essential step in learning…

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