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Postdoctoral Fellow

Gyubum Lim

Postdoctoral Fellow

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Meiosis is a cell division process to generate gametes by two consecutive cell divisions in all sexually reproducing organisms. During prophase of the first meiotic division, programed DNA double strand break is repaired by homologous recombination and it becomes crossover. Crossover not only generates genetic diversity but also provides a direct connection between homologs that is required for accurate segregation. Interestingly, crossovers tend to be well-spaced along the chromosomes and it is achieved by the phenomenon called crossover interference. As a postdoctoral researcher in Nancy Kleckner’s lab, I am interested in the factors that can affect crossover interference and crossover patterning on meiotic chromosomes. My work will provide better understanding of the regulatory mechanism of crossovers and meiosis.