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Tag: Erin O'Shea

ROBUST CLOCKS IN GROWING BACTERIA [O’SHEA LAB]

(l to r) Sophie de Buyl, Shu-Wen Teng, Jeffrey R. Moffitt, and Shankar Mukherji with Nikhil Living organisms tightly coordinate their physiology with the day and night cycle.…

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MOLECULAR CLOCKWORK OF BACTERIAL TIME-KEEPING [O’SHEA LAB]

Erin O'Shea (l) and Andrian Gutu The day-night cycle is the most predictable environmental variation on Earth. Many organisms, ranging from bacteria to humans have evolved endogenous time-keeping…

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MODULARITY OF TRANSCRIPTION FACTORS ENABLES MULTIFUNCTIONAL SIGNAL PROCESSING [O’SHEA LAB]

Nan Hao (l) and Erin O'Shea Living organisms respond to external cues and initiate appropriate physiological responses through activation of transcription factors, which regulate expression of target genes.…

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ERIN O’SHEA: HHMI VICE-PRESIDENT FOR SCIENCE AND CHIEF SCIENTIFIC OFFICER

Erin O'Shea The prestigious Howard Hughes Medical Institute has named Erin K. O’Shea as Vice-President for Science and Chief Scientific Officer. O’Shea is the director of the Harvard…

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PROF. ERIN O’SHEA’S ZAMBO KEEPS ON WINNING

Last year, we wrote about MCB Professor Erin O'Shea’s championship dog, Zambo, and his victory at the Universal Sieger World Championships in Austria where he received the world’s…

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ERIN O’SHEA’S DOG ZAMBO WINS WORLD CHAMPIONSHIP

Erin K. O'Shea and Zambo   Erin O'Shea is a world leader in studies of gene regulation, but a world champion? That’s a title reserved for her German…

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CISCODE, TRANS EFFECT, TRANSCRIPTION SPECIFICITY

Erin K. O'Shea and Xu Zhou Gene expression is controlled by a class of proteins called transcription factors. These proteins usually bind to short 6-8 base pair DNA…

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BACTERIAL CIRCADIAN CLOCKS TIGHTLY LINKED TO METABOLISM

Michael J. Rust and Erin K. O'Shea Circadian clocks are biological oscillators that help organisms keep track of the time of the day and coordinate their behavior with…

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DISSECTING TRANSCRIPTIONAL NETWORK STRUCTURE AND FUNCTION

Andrew Capaldi and Erin O'Shea The gene expression program in a cell is set in response to the level, timing and combination of hundreds of developmental and environmental…

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A QUANTITATIVE MODEL OF TRANSCRIPTION FACTOR–ACTIVATED GENE EXPRESSION

Erin O'Shea, and Harold Kim One of the main challenges in the postgenomic era is to understand how genetic information is translated into quantitative transcriptional output. Transcription factors…

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