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Tag: Publication

How a “Spot the Difference” Technique Illuminates the Wiggling of Proteins

It’s common to speak of “the structure of a protein,” but proteins are dynamic molecules that move and shapeshift.  A protein can be described as 1-dimensional polymer –…

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Nature Over Nurture: Functional Neuronal Circuits Emerge in the Absence of Developmental Activity [Engert Lab]

Understanding how functional neuronal circuits are established during development is a fundamental challenge in neuroscience. During development, the complex neuronal circuitry of the brain arises from limited information…

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How Neuron Types Work Together to Process Punishment and Reward [Uchida Lab]

As they navigate their environment, animals readily learn to repeat actions which yield reward and avoid actions which cause punishment. This kind of learning is especially efficient when…

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MCB Sanes Lab Is One of Six Harvard Labs Contributing to Cell Census Network

MCB faculty Joshua Sanes is part of a coalition of scientists who are attempting to map and characterize all of the cell types present in mammalian brains. His…

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Giri Anand’s Curiosity Unlocks New Info on How Cells Behave [Ramanathan Lab]

Giri Anand’s path to studying biology started when he first got his hands on a copy of James Watson’s “Double Helix” as an AP Biology student at Newton…

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Plants Repurpose a Textbook Enzyme to Build Neuroactive Medicines [Nett Lab]

Plants are well known for their ability to produce molecules that affect human cognition, including many drugs for treating neurological disease. However, we understand relatively little about how…

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DNA Folding Choices Made in Stem Cells Determines How Genes are Expressed in the Brain [Whipple Lab]

A new study led by MCO graduate student Daniel Loftus of the Whipple Lab has found that differences in maternal and paternal genomes in embryonic stem cells shape…

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To Sting or Not to Sting: How Changes to an Ion Channel Shape Sea Anemone Stinging [Bellono Lab]

Sea anemones are known for stinging, but not all anemones sting alike. By comparing two related anemones, the Bellono Lab has identified a small change in how a…

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Raising a Translation Factor: A Novel Co-chaperone Family Guides eEF1A to Maturity [Denic Lab]

All cells contain a network of molecular chaperones that help other proteins (often called “clients”) fold into functional three-dimensional conformations. Decades of research on chaperones has led to…

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The Eyes Have It [Sanes Lab]

Vision begins in the retina, a part of the brain that lines the back of the eyeball. It contains complex neural circuits composed of numerous cell types that…

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