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How Experience Shapes the Social Brain—One Tiny Fish at a Time

Why do animals respond differently to the same social situation? According to new research from the MCB lab of Florian Engert, the answer may depend as much on…

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New CRISPR Method Reveals Genes That Shape the Developing Brain

Understanding how a single genetic mutation can alter the shape of a developing organ has long posed a challenge for developmental biologists. While researchers can readily study the…

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Two Decades in the Making: New Study Reveals How Brain Function Shapes Its Own Structure

After nearly 20 years of meticulous research, a team of Harvard scientists has published findings in Nature Neuroscience (PDF) that fundamentally challenge how we think about brain development.…

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Mapping the Sense of Smell, Molecule by Molecule

A new study from the lab of Catherine Dulac, the Xander University Professor of Molecular and Cellular Biology at Harvard, in collaboration with Xiawei Zhuang of Harvard’s Departments…

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Small Model, Big Insight: RNA Structure Rules Emerge from Minimal Data

MCB Senior Research Fellow Elena Rivas and colleagues have demonstrated that the fundamental rules governing RNA structure can be learned using a remarkably simple computational model—challenging assumptions that…

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Study Reveals Octopus Mating Arm Doubles as a Chemical Sensor

A new study (PDF) from the MCB lab of Nicholas Bellono reveals an unexpected sensory mechanism underlying octopus reproduction—showing that a specialized arm used for mating is also…

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ROCKET Launches Structural Biology Past AlphaFold

Five years ago, a team at Google’s DeepMind won CASP14, the long-running protein structure prediction competition, with AlphaFold, a machine-learning system capable of predicting the three-dimensional structures of…

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Evolutionary Clues Reveal How a Key Hearing Protein Adapted for Function

A new study in Current Biology (PDF) sheds light on how a critical protein underlying hearing evolved to perform its specialized role in vertebrate sensory systems—offering a rare…

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Why Evolution Keeps Returning to the Same Solution for Smell

Why do animals as different as insects and mammals process smells in nearly the same way? A new theoretical study published in PNAS takes on this question by…

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Study Reveals Neural Circuit Behind the Brain’s Dopamine–Serotonin “Gas–Brake” System for Reward

A new study by Daniel Cardozo Pinto, now a Harvard Junior Fellow in MCB, has uncovered a neural circuit mechanism explaining how two key brain chemicals—dopamine and serotonin—work…

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