Resources Directory
Assistant Professor of Molecular and Cellular Biology and of Applied Physics

Maxim Prigozhin

Assistant Professor of Molecular and Cellular Biology and of Applied Physics

Back to Faculty Profiles

Multicolor and time-resolved electron microscopy of cell signaling

Electron microscopy is an ideal imaging technique to study biological cells at the nanoscale. However, typically electron microscopy only provides static black-and-white images. In an effort to enable multicolor and time-resolved electron microscopy, my laboratory will develop dedicated molecular probes and instrumentation for new correlative light and electron microscopy modalities, and build next-generation biophysical tools for time-resolved cryo-vitrification and high-resolution imaging of cells. These methods will be used to elucidate the nanoscale protein and membrane dynamics of G protein-coupled receptor (GPCR) signaling in differentiated cells and complex tissues.

Selected Publications