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Undergraduate Molecular and Cellular Biology (MCB) Research and Thesis

Research and Thesis

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  • Thesis Timeline

    A senior thesis is a year-long research for credit course worth 8 credits and is letter graded. Students must identify a faculty sponsor that is willing to host and mentor them latest by the end of Spring semester of Junior year (students may decide to start earlier) since the thesis proposal is due mid-July before senior year. Faculty sponsors must be a Harvard faculty or an affiliate of Harvard. Once your proposal is accepted, you may enroll in MCB/CPB 99AB. Students enrolled in 99AB are expected to work ~15 hours/week during term time. Research mentors are expected to provide training on both the science and writing. The undergraduate office will provide supplemental support by hosting a number of workshops and exercises aimed at improving the quality of presentation and writing.

  • MCB Thesis 2021
    • The Regulation of Neuronal Protein Turnover and Aggregation Through the Neuroproteasome Bafia, Joanna PI: Ramachandran, Kapil
    • The Role of the MiT/TFE Family of Transcription Factors in the Pathogenesis of TSC and BHD  Boku, Yoseph PI: Henske, Elizabeth
    • Barth Syndrome Drug Repurposing Screen Cotton, Justin O’rion PI: Pu, William
    • Cellular Effects of Overloading Proteasome Capacity in Human Disease Dasarathy, Dhweeja PI: Goldberg, Alfred
    • Characterization of Ebolavirus Transcriptional Regulatory RNA Structures Edwards, Jerome PI: D’Souza, Victoria
    • Computational Profiling of Two Microbial Superoxide Dismutase Superfamilies in the Human Gut Microbiome Hamad, Leena PI: Balskus, Emily
    • Agent-Based Modeling of the 2009 H1N1 Pandemic and Exploration of Application to the COVID-19 Pandemic Hill, Nathan PI: Sabeti, Pardis
    • Deconvulving Bulk RNA-seq to Create a Temporal Map of Ebola Virus Disease Lopez, Emily PI: Sabeti, Pardis
  • MCB Thesis 2020
    • Identifying CD8+ Dendritic Cells and Lysophosphatidic Acid as Modulators of T cell recruitment to Melanoma in Danio Rerio Afeyan, Alexander PI: Zon, Leonard
    • Mutations in PPM1D Characteristic of Clonal Hematopoiesis of Indeterminate Potential Modulate Inflammatory Signaling Through HMGA2 Altshuler, Zachary PI: Ebert, Ben
    • Understanding how cis-regulatory DNA enhancer elements are altered in FOG2-mediated atrial fibrillation  Butler, Catalina  PI: Pu, William
    • Multi-task learning of Bayesian networks identifies candidate causal proteins in neurodegenerative diseases  Cousins, Clara PI: Fraenkel, Ernest
    • Effects of early life stress on female mice social behaviors  De Leon, Maria  PI: Hensch, Takao
    • Lem2 Aggregation:  Deleterious Function Within and Beyond the ESCRT-III Pathway  Dempsey, Nathaniel PI: Pellman, David
    • Transcriptome Profiling of Muller Glia in the rd1 Mouse Model of Retinitis Pigmentosa and The Development of Probe-Seq Garcia, Mauricio PI: Cepko, Connie
    • Recapitulating Differentiation Blockade in Osteosarcoma Gibbons, John  PI: Scadden, David
    • Using Ago-Loading to Identify miRNAs and mRNAs Involved in the Regulation of Activity-Dependent Synaptogenesis  Gowravaram, Niket PI: Van Vactor, David
    • Applying Mediation Analysis to Predict Feed Forward Loops as Gene Regulatory Mechanisms in Multiple Myeloma – A Novel Statistical Approach  Han, Tessa  PI: Parmigiani, Giovanni
    • Development of a Point-of-Care Diagnostic Test for Borrelia Miyamotoi, an emerging tick-borne pathogen, using CRISPR Cas13a  Hua, Catherine PI: Sabeti, Pardis
    • Control of Pancreatic Beta Cell Maturation by the Circadian Factor Sharp2 Montalvo, Ana PI: Melton, Doug
    • Synthesis and Biomolecular Reactivity Preferences of Fluorinated Aryl Diazirines  Parsons, Matthew PI: Woo, Christina
    • Role of miRNAs, T Cell Activation, and Estrogen in Splicing Factor SRSF1 Expression in Systemic Lupus Erythematosus Ramanujan, Suruchi  PIs: Multon, Vaishali and Tsokos, George
    • A Comparative Analysis of RNA Sequencing Techniques to Understand Progression of Kidney Fibrotic Injury  Rane, Sanjana PIs: Valerius, Todd and Bonventre, Joseph
    • The Protective Role of Intestinal Alkaline Phosphatase Against NSAID-Induced Intestinal Damage Record, Sydney  PI: Hodin, Richard
    • Development of a Cell-Type Focused Hidden Markov Random Field Model to Dissect the Intrinsic and Extrinsic Contributions to Cellular Heterogeneity  Sarkar, Arpan PI: Yuan, Guo-Cheng
    • The Role of Inflammatory Factors in Zebrafish Melanoma Saydahmat, Gulenay  PI: Zon, Leonard
    • A Sparse Classifier for Heirarchical Data: Interpretable Deep Learning for ALS Genomic Analysis  Sebenius, Isaac PI: Fraenkel, Ernest
    • Microbiota Regulation of Intestinal Eosinophils  Villarreal, Jannely  PI: Garrett, Wendy
    • Determining the Mechanism of the Suppression of OSpB Activity by Bre1Overexpression Yoon, Jessica Myungseo PI: Goldberg, Marcia
  • MCB Thesis 2019
    • Degradation of Adeno-Associated Virus Viral Proteins Through the UBiquitin Proteasome Pathway Cepeda Diaz, Ana Karla PI: Vandenberghe, Luk
    • A Unique Population of Peyer’s patch iNKT cells: An investigation of its function Chen, Gui Zhen PI: Dougan, Stephanie
    • Promiscuity and Specificity of Clustered Protocadherin Binding Interfaces Chiang, Brenda PI: Gaudet, Rachelle
    • FLT3-ITD Activates Malic Enzyme 2 and Reprograms Acute Myeloid Leukemia Choi, Una PI: Scadden, David
    • Additional Candidate Genes in Agenesis of the Corpus Callosum and Related Disorders Comrie, Cameron PI: Yu, Timothy
    • Characterization of interclonal cooperation within the triple negative breast cancer cell line MDA-MB-468 Crowdis, Jett PI: Brugge, Joan
    • Genomic Signatures of Development
      and Plasticity in the Primary Auditory Cortex
      DeMessie, Bluye PI: Hensch, Takao
    • Investigation of the Roles of MHC Class II and Selected Signaling Molecules in the Induction of Regulatory T Cells by Plasmacytoid Dendritic Cells Gibney, Sean PI: Allesandrini, Allesandro
    • Regulation of small nucleolar RNAs in chemo-resistant cancer cells Granovetter, Madeleine PI: Vasudevan, Shobha
    • Automatic Behavior in Musicians Kim, Erin PI: Duffy, Jeanne
    • Investigating the Therapeutic Potential of CDK12 Inhibition in Osteosarcoma Lu, Jim PI: George, Rani
    • Viral Origami: Investigating the Secondary Structure and Evolution of Ebola virus RNA Luo, Cynthia PI: Sabeti, Pardis
    • A novel method to expand CAR T cells via an LDL receptor knockout artificial antigen-presenting cell Marsh, Leah PI: Maus, Marcela
    • Using patient-derived iPSC models to investigate skeletal muscle formation defects in Spinal Muscular Atrophy Mazumder, Soumyaa PI: Rubin, Lee
    • Maternal Vaccination to Boost Neonatal Immunity Noelette, Francesca PI: Alter, Galit
    • Macrophages and T cells in the Regenerating Limb of the Ambystoma mexicanum Oshiro, Rachel PI: Whited, Jessica
    • Towards a Deep Learning Based Homology Search Tool: Inferring RNA structure from homologous sequences with Deep Neural Networks Paul, Steffan PI: Eddy, Sean
    • An Early Investigation into the Biology of USP7, a Deubiquitinating Enzyme, with the Potential for Small Molecule Inhibition in Cancer Treatments Perera, Sumner PI: Buhrlage, Sara
    • Role of C9ORF72 in vascular endothelial cell structure and maintenance in ALS Rao, Bovey PI: Eggan, Kevin
    • The Mammalian Cardiomyocyte Proliferative State and Investigating Its Effective on Sarcomere Structure Reyes, Karen PI: Li, Richard
    • Response of Plasmodium falciparum to a Novel Class of Antimalarials:
      The Role of DHODH Mutation in Resistance and Fitness
      Reynolds, Matthew PI: Wirth, Dyann
    • Peroxisome Insertion of a Membrane Protein by Matrix Protein Import Machinery Tam, Hanson PI: Denic, Vladimir
    • Determining the role of bacterial protein BefA in promoting mammalian pancreatic islet expansion Tran, Melissa PI: Kostic, Aleksander
    • The TLR9 Ligand CpG Oligonucleotide Reduces Cytotoxic T Lymphocyte-mediated Cardiac Injury Wara, Nafisa PI: Lichtman, Andrew
    • Characterizing the regulatory role and structural significance of the IGR5 small RNA in Mycobacterium smegmatis Xu, Rachel PI: Fortune, Sarah
    • Assessing the Role of Monocytes in Smoking-Induced Susceptibility to Tuberculosis Yan, Allison PI: Kwon, Douglas
  • MCB Thesis 2018
    • Endogenous Gene Modulation by Direct Delivery of Zinc Finger Artificial Transcription Factors Allen, Jackson PI: Joung, Keith
    • Characterizing the Role of Intratumor Heterogeneity in Triple Negative Breast Cancer Drug Resistance Amich, Jose PI: Brugge, Joan
    • PrPC Binds Soluble Aggregates of Tau and α-Synuclein Asfaw, Adhana PI: Walsh, Dominic
    • Assessing the Glycosignature of Exosomes Derived from a Human Colon Cancer Cell Line Castillo, Gerardo PI: Sackstein, Robert
    • Exercise Induces the Birth of New Cardiomyocytes in the Adult Mammalian Heart Gonzalez, Emilia PI: Lee, Richard
    • Characterizing the Role of idsE In Vivo in Populations of Proteus mirabilis Hao, Amy PI: Gibbs, Karine
    • Towards higher standards for quality control and analysis of single-cell Hi-C data Horton, Connor PI: Park, Peter
    • Generating Alveolar Rhabdomyosarcoma in Danio Rerio Jin, Alexander PI: Langenau, David
    • Genetic and Pharmacological Corrections of Aberrant α-Synuclein Homeostasis Kantor, Elizabeth PI: Dettmer, Ulf
    • The Role of IdrE in an Effector/Immunity System of Proteus mirabilis Keteku, Emma PI: Gibbs, Karine
    • Creation and Characterization of an Isogenic G6PD Deficiency Model System Lopez, Ashley PI: Duraisingh, Manoj
    • Targeting MUC1-C Suppresses EZH2 Through an NF-κB p65 and MYC Dependent Mechanism Markert, Tahireh PI: Kufe, Donald
    • Identifying the Regions at which IMP2 Regulates Myc mRNA Translation Narayan, Priyanka PI: Weissleder, Ralph
    • A Structure-Function Analysis of IdsE, a Self-Identity Protein Involved in the Self -and Non-Self-Recognition System of Proteus mirabilis Pinnock, Akeem PI: Gibbs, Karine
    • RNA methylation regulates viability and translation in chemoresistant cancer cells Plotsker, Ethan PI: Vasudevan, Shoba
    • Generation and Characterization of Novel Anti-PD1 Antibodies for Cancer Immunotherapy Qiu, Mengting PI: Alt, Frederick
    • Identification and Characterization of a Novel RNA-Dependent RNA Polymerase Mutation and Its Impacts on RNA Interference (RNAi) in Caenorhabditis elegans Reddy, Neha PI: Hunter, Craig
    • Investigating the Activity and Regulation of CTD Phosphatases Saganty, Rachel PI: Buratowski, Stephen
    • Therapeutic fusion proteins for targeted immune suppression Siraj, Yasmin PI: Silver, Pamela
    •  Modeling and Investigating the Effects of CC-885 in Murine Cells Sullivan, Aurora PI: Ebert, Benjamin
    • Follistatin-like 3 and regulation of age-related cardiac hypertrophy Yamada, Jessica
    • A Non-Processive PBP2 Mutant Enables Novel Insight into Glycosyltransferase Activity and Inhibition in MRSA Yang, Alan PI: Kahne, Daniel
  • MCB Thesis 2017
    • A Characterization of the Guanylate Binding Proteins During C. trachomatis Infection Harrison, Noah PI: Starnbach, Michael
    • The killer lymphocyte protease granzyme B disrupts protein chaperones in bacteria Binker Cosen, Andy PI: Lieberman, Judy
    • Profiling the DNA Specificity of Recombinases by in vitro Selection and High-Throughput DNA Sequencing Afeyan, Lena PI: Liu, David
    • Changes in Genetic Instability and Cellular Fitness via Experimental Evolution of Saccharomyces Cerevisiae Armenta, David PI: Murray, Andrew
    • Targeted genome editing to replicate loss-of-function variants: A pathway for exploration of novel therapeutic approaches for Parkinson’s and Huntington’s diseases Ashrafzadeh, Sahar PI: MacArthur, Daniel
    • Towards an Age-Dependent Study of Innervation Patterns of Lymph Nodes Austin, John PI: von Andrian, Ulrich
    • Dissecting the Antigen Presentation System During Infection Brooks, Donald PI: Chevrier, Nicolas
    • A Wnt-Dependent Model of Synaptic Organization in the Outer Retina Cousins, Henry PI: Sanes, Joshua
    • Characterizing a Novel Mouse Model of Inducible Lubricin Deficiency and its Implications for Osteoarthritis Coyan, Mara PI: Warman, Matt
    • Investigating adaptive aminoglycoside resistance in Pseudomonas aeruginosa Cummins, Kaelyn PI: Hung, Deborah
    • Investigating the Role of Dual Inhibition of Histone Deacetylase and Lysine Specific Demethylase 1 in the Context of Diffuse Intrinsic Pontine Glioma Kim, Mirhee PI: Shi, Yang
    • A computational approach for classifying nervous system cell subtypes using single-cell mRNA expression profiles Lin, Victoria PI: McCarroll, Steven
    • Biochemical Characterization of BAM7 Derivatives as Molecular Modulators of Pro-Apoptotic BAX Linskey, Eamon PI: Walensky, Loren
    • Scalable Biofabrication of Vascularized Human Liver Tissue Nam, Thuy PI: Lewis, Jennifer
    • Sleep and Aging: Associations and Causation between Leukocyte Telomere Length, Sleep Duration, and Sleep-Related Genetic Variants Onion, Zoe PI: Czeisler, Charles
    • Pursuing Synergy: Combining a Pan-Class PI3K Inhibitor with Novel Small Molecule Inhibitors of c-Myc Ors, Muhammed PI: Koehler, Angela
    • Identifying Neurologically Relevant Substrates of Vaccinia-Related Kinase 2 Sha, Carrie PI: Schier, Alexander
    • Negative Regulators of p53 as Vulnerabilities in SWI/SNF-Mutant Cancers Song, Melinda PI: Hahn, William
    • Enabling Natural Killer Cell Cancer Immunotherapy Using CRISPR-Cas9 Deletion of Inhibitory Receptor Genes Vora, Kruti PI: Cowan, Chad
    • Divide and Conquer: Investigating the Role of FtsQ in Regulating Cell Division in Mycobacterium Smegmatis Zhang, Jenna PI: Rubin, Eric
    • Using iPSC-derived neurons to model cell fate-specific effects of Alzheimer’s disease Zhou, Constance PI: Young-Pearce, Tracy
    • Genomic characterization of urethritis-associated Neisseria meningitidis Ma, Kevin PI: Grad, Yonatan
    • Patterns of murine T follicular helper cell differentiation Murphy, Samuel PI: Pillai, Shiv
    • Understanding Regulation of Splicing During the Innate Immune Response Yu, Kimberley PI: Burge, Chris
    • From Depolarization to Neuronal Differentiation: Analysis of Npas4, Npas3 and Arnt2 in Hippocampal Development Jowell, Amanda PI: Greenberg, Michael
    • Development of a Macro-Organoid Explant Bioreactor for a Colorectal Cancer Xenograft Platform Fulop, Daniel PI: Traverso, Giovanni
  • MCB Thesis 2016
    • Characterization of the Mitochondrial Permeability Transition and Localization of Cyclophilin 1 in Drosophila melanogaster Artiga, Daniel PI: Clapham, David
    • A Functional Analysis of GDF5 Enhancers using CRISPR/Cas9-mediated Genome Editing Ahmed, Eman Riaz PI: Capellini, Terrence
    • The True Powerhouse of the Cell: The Role of Neuronal Glycolysis in Acute Metabolic Stress During Glucose and Ketone Body Metabolism Bose, Shree PI: Yellen, Gary
    • Identification of a novel factor(s) regulating listeriolysin O (LLO) expression in Listeria monocytogenes in response to serum Cornelius, Rachael PI: Higgins, Darren
    • The Role of p63 in Regulating Hair Regeneration Hanna, Yousif PI: Ellisen, Leif
    • Elucidating Mechanisms of Histone Methylation with a RNA Polymerase-Tethered Histone Lysine Methyltransferase He, Philip PI: Buratowski, Stephen
    • Investigating a rebound in Plasmodium falciparum transmission using molecular barcoding Irvine, Caleb PI: Wirth, Dyann
    • The Role of DNA Binding in the Repression of Fetal Hemoglobin by BCL11A Jean-Louis, Gaston PI: Orkin, Stuart
    • Identifying a Macrophage-dependent Mechanism of Post-extravasation Survival of Metastasized cells Pant, Ayush PI: Weinberg, Robert
    • DDX3X mutations result in a dose-dependent increase in capindependent
      protein translation in medulloblastoma Selwa, Katherine PI: Pomeroy, Scott
    • Reconstitution of HIV-1 Envelope Glycoprotein into Nanodiscs for Vaccine and Structural Studies Witt, Kristen PI: Sodroski, Joseph
  • MCB Thesis 2015
    • Interrogation of cricket germ line development by Wnt Pathway knockdown Johansson, Kimberly PI: Extavour, Cassandra
    • Investigating the functional significance of Firre in pluripotency and reprogramming Park, Daniel PI: Rinn, John
    • Investigating idic15 autism phenotype reversibility in an adult genetic rescue mouse model Silva, Michael PI: Anderson, Matthew
    • Autophagy inhibitor screen provides new drug development options and insight into pathway interactions Li, Selena PI: Yuan, Junying
    • Characterization of a putative nucleoid-associated protein, YaaK, in Bacillus subtilis Tang, Olive PI: Rudner, David
    • Combinatorial molecular labeling defines a new retinal ganglion cell type Kagan, Ruth PI: Sanes, Joshua
    • The Role of Olfactory Marker Protein (OMP) in Proper Glomerular Convergence of Olfactory Sensory Neuron Axons Agarwal, Prateek PI: Murthy, Venkatesh
    • The TRPC5 ion channel is a critical modulator of podocyte injury. Tarabanis, Constantine PI: Greka, Anna
    • Genetic Requirements for Environmental RNAi Elkington, Joshua PI: Hunter, Craig
      Analyzing Dietary Treatments for Epilepsy: From Galen to Modern Research Glasser , Rebecca PI: Yellen, Gary
    • Thioredoxin-interacting protein may cause cortical cell dysfunction in diabetes-related dementia Kushman, Arielle PI: Lee, Richard
    • Lncing RNA to FXR1: FXR1 modulates expression of Xist Quartey, Qaren PI: Vasudevan, Shoba
    • Synectin binds the Plexin D1 carboxy-terminal PDZ-binding motif and regulates Semaphorin 3E-mediated inhibition of MAPK signaling Kelly, Ryan PI: Klagsbrun, Michael
  • MCB Thesis 2014
    • Adenovirus Serotype 5 (Ad5) Versus Alternative Serotype Adenovirus Vaccine Vectors: Comparative Analysis of CD8 T Cell Responses Ra, Joshua PI: Barouch, Dan
    • Slowing Aging and Infertility with the CD38 Inhibitors Apigenin and Luteolin Simmons, Kristen PI: Sinclair, David
    • Structural Patterns of Synaptic Competition in the Motor Neuron Circuit Boothby, Ian PI: Lichtman, Jeff
    • Impact of Irregular Slee-Wake Patterns and Associated Light Exposure on Entrainment of Circadian Neuroendocrine Rhythms and Physiology in College Undergraduate Students Clerx, William PI: Czeisler, Charles
    • Structural Characterization of the SARS Translational Recoding Mechanism D’Gama, Jonathan PI: D’Souza, Victoria
    • High-throughput analysis of protein-DNA binding using next-generation sequencing Genuth, Naomi PI: Church, George
    • Exploring pathogenicity in the clinical isolate U2504 of Pseudomonas aeruginosa Gorbachuk, Nataliya PI: Hung, Deborah
    • MEF2D is required for retinal photoreceptor development and regulates genes critical for proper rod architecture Lee, Charlotte PI: Greenberg, Michael
    • Investigating the Coordination of Septation and Elongation in Mycobacteria through Characterization of MSMEG_4234, a Potential Cell Division Player Leung, Vivian PI: Rubin, Eric
    • Screening and Characterization of Novel Regulators of Hepcidin Expression Volovetz, Josephine PI: Fraenkel, Paula
    • Tumor collagen and cancer-associated fibroblasts hinder cancer immunosurveillance by controlling the localization of tumor-infiltrating T cells Wu, Michael PI: Turley, Shannon
    • Engineering a Light-Sensitive Circadian Clock Yeong, Vivian PI: Silver, Pamela
      Core cellular surveillance in C. elegans is coupled to systemic xenobiotic detoxification response via bZIP transcription factor ZIP-2 and p38 MAP-kinase signaling Zhang, Xinrui PI: Ruvkun, Gary
    • Identifying Mutations That Modulate Drug Sensitivity Using Systematic Single Codon Substitution Moore, Nicholas PI: Kishony, Roy
  • MCB Thesis 2013
    • Identification of CEP-701 as a Small Molecule Regulator of Satellite Cell Proliferation through High-Content Screening Smart, Alicia PI: Rubin, Lee
    • Induction of Autoinflammatory Signaling in Genomically Unstably Cells by Perturbations in the Endogenous Nuclease DNase2 Dockterman, Jacob PI: Hacohen, Nir
    • Evaluation of small-molecules for abilities to reverse the effects of leflunomide on neural crest progenitors Xia, Fan PI: Zon, Leonard
    • Primordazine Induces Translational Repression via a 120 Nucleotide Response Element in the Zebrafish Nanos1-3’UTR Gonzales, Andrew PI: Peterson, Randell
    • Examining the mechanism by which liver-specific microRNA-122 modulates apolipoprotein B-100 Lin, Carol PI: Chung, Raymond
    • The critical role of host lipid metabolism in determining the infectivity of Hepatitis C virus Meixiong, James PI: Chung, Raymond
    • BACE, the β-secretase of Amyloid Precursor Protein-Like, is Required for Long-Term Memory in Drosophila melanogaster Liu, Carol PI: Kunes, Samuel
    • Improving the efficiency and fidelity of RNA-catalyzed polymerization: Implications for 2-thio-uracil in the RNA world Michaels, Yale PI: Szostak, Jack
    • Investigating the Mechanism of SpoIIIE Mediated End-loop Resolution in Sporulating Bacillus subtilis. Barnes, Leandra PI: Burton, Briana
    • α-secretase and γ-secretase associate together during regulated intramembrane proteolysis of APP Patel, Sarvagna) PI: Selkoe, Dennis
    • Transcriptional control of hair follicle regeneration by p63 Yarabe, Paul Ellisen, Leif
      Interactions Between Host Genetics, Host Diet, and the Gut Microbiota in Response to Diet Shifts Luevano, Jesus PI: Turnbaugh, Peter
    • Knockdown of Maternal Embryonic Leucine Zipper Kinase and the Effects on Ovarian Cancer Cells in vitro: Assessing the Potential of MELK as a Therapeutic Target in Ovarian Cancer Choi, Christine PI: Zhao, Jean
    • Translation without a poly(A) tail Hadar, Peter PI: Gehrke, Lee
      Identification, sequencing and characterization of four putative systemic RNAi proteins Yao, Lisa PI: Hunter, Craig
    • The Role of Sonic Hedgehog in the Development and Maintenance of the Mammalian Olfactory System Persson, Laura PI: Segal, Rosalind
    • Effects of Translation on Mitotic Spindles Lutfeali, Reshma PI: Blower, Michael
    • The transcription factor BATF3 may be a novel regulator of angiogenesis and breast cancer progression: An in vitro and in vivo study Stein, Elliot PI: Moses, Marsha
    • The Effect of Neostriatal Dendritic and Synaptic Alternations on Glutamate Toxicity in a Huntington’s Disease Knock-in Mouse Model Lin, Amy PI: Difiglia, Marian
    • Shigella effector OspC3 enhances intracellular replication in minimally type 3 secretion competent bacteria Polachek, William PI: Lesser, Cammie
  • MCB Thesis 2012
    • Programming modification of multivalent nanoparticle surfaces with DNA Guan, Xin PI: Yin, Peng
    • The Role of in Integrins α4β1 and α4β7 in the Migration of Pathogen-Specific CD4+ T Cells to the Genital Tract of Mice Infected with Chlamydia trachomatis and Creating a CEL1 Nuclease-based Assay to Identify Null Mutants in Chlamydia trachomatis Allison, Christopher PI: Starnbach, Michael
    • A Direct Interaction between Yos9p and Hrd3p Promotes Oligomerization of a Membrane Complex Responsible for Endoplasmic Reticulum Associated Degradation of Luminal Proteins Anghel, Stefan PI: Rapoport, Tom
    • The LRP5 Pathway in Osteogenesis Imperfecta Therapeutics Barber, Lauren PI: Warman, Matt
    • p63-dependent regulation of epithelial basal cell adhesion protein genes in permissive somatic cell types Bunker, Lydia  PI: Rheinwald, James
    • MicroRNA-26b in Alzheimer’s Disease (AD): A potential regulator of cell cycle and apoptosis in post-mitotic neurons Cho, Hyunje PI: Krichevsky, Anna
    • Role of Bmi1 in Regulating Cardiac Myosin Heavy Chain Expression Dong, Xuezhi PI: Jackson-Grusby, Laurie
    • Phenotypic Analysis of Sid-3 structure and function in RNA interference Ekman, John Steven PI: Hunter, Craig
    • The Development of a Novel Inducible Foxn1 Reporter: Generation, Characterization, and Applications Feng, Jeremy PI: Melton, Doug
    • Identification and characterization of proteins required for the regulation of microtubule-based transport Heer, Natalie PI: Reck-Peterson, Sam
    • “Excitatory Projection Neurons Subtypes Controls the Distribution
      of Local Inhibitory Interneurons in the Cerebral Cortex Jantrachotechatchawan, Chanati PI: Arlotta, Paola
    • The DAQ Knight and the Secret Life of Dopamine: The Effects of Dopamine Quinone on in vitro α-synuclein Ubiquitination by Nedd4 Kogan, Edward PI: Goldberg, Alfred
    • Developing a genetic approach to induce Trichomonas Vaginalis Virus infection in T. vaginalis. Kula, Tomasz PI: Nibert, Max
    • A Real-Time, Live-Cell microRNA Reporter Library Identifies microRNA Actors in Non-Genetic
    • Drug-Resistance Networks Leya, Gregory PI: Brugge, Joan
    • Integration of the ER and Oxidative Stress Responses through SKN-1 Lin, Stephanie PI: Blackwell, Keith
    • 53BP1 Regulates the Aurora A/TPX2 Complex Luo, Yuying PI: Shi, Yang
    • Investigation of SAP-1 activity in Caenorhabditis elegans Madubata, Chinwe PI: Mango, Susan
    • Disease modeling of amyotrophic lateral sclerosis (ALS): Morphometric analysis of motor neurons derived from induced pluripotent stem cells and functional characterization of astroglia derived from human embryonic stem cells Mikkilineni, Shravani PI: Eggan, Kevin
    • Translational genetic recoding by viral mRNA pseudoknots Nagle, Julia PI: D’Souza, Victoria
    • Dendritic Cell Immunoreceptor (DCIR) silencing using CD4 aptamer-DCIR siRNA chimeras:a model to investigate mucosal transmission of the Human Immunodeficiency Virus (HIV) Onofrey, Lauren PI: Lieberman, Judy
    • Understanding the biological risk of chromosome 4 locus triplication for Parkinson’s Disease Perez-Torres, Eduardo PI: Isacson, Ole
    • Characterization of Dysfunctional Mitochondrial Stress Response in Parkinson’s Disease Prager, Briana PI: Isacson, Ole
    • The Search for Novel Sporulation Genes in Bacillus subtilis Pugliese, Antonia PI: Losick, Richard
    • Effects of the Loss of Red-Cone Photoreceptors on Cone Mosaic Formation and Horizontal Cell Morphology in Zebrafish (Danio rerio). Qi, Robert PI: Dowling, John
    • Revealing Downstream Effectors of the Target of Rapamycin Complex 2 (TORC2) Pathway Using RNAi and Lifespan Analysis: An examination of different Caenorhabditis elegans phenotypes Runcie, Mariama PI: Soukas, Alexander
    • Investigating small molecules that bind p16INK4a and their effects on cellular senescence Sandler, Jason PI: Shaw, Stanley
    • Targeting Casein Kinase 1 and 2 to inhibit invasion of red blood cells by the human malaria parasite, Plasmodium falciparum Sarma, Nandini PI: Duraisingh, Manoj
    • Developmental Basis of Craniofacial Variation in Anolis Carolinensis Seav, Susan PI: Abzhanov, Arkhat
    • A Split-Intein Based Approach to Protein Sensing in Mammalian Cells Selgrade, Daniel PI: Silver, Pamela
    • Probing functional consequences of the lprG/Rv1410c double knockout in Mycobacterium bovis Bacille Calmette-Guérin Sullivan, Zuri PI: Rubin, Eric
    • Identification of immunogenic Salmonella enterica serotype Paratyphi A proteins uniquely expressed in humans and not under standard laboratory conditions Tsai, Lillian PI: Ryan, Edward
    • The role of Protein Phosphatase 2A in HIV-Specific Human T Cell Dysfunction Virgin-Downey, Herbert PI: Kaufmann, Daniel
    • Netrin-1 Promotes Glioblastoma Invasion and Angiogenesis Through a Cathepsin B-Dependent Mechanism Wang, Priscilla PI: Klagsbrun, Michael
    • Translational Frameshifting in Trichomonas Vaginalis Virus Wang, Shitong PI: Nibert, Max
    • CD1 Modulation of Decidual Immune Cell Activity Wu, Vernon PI: Strominger, Jack
    • A STAT3-iNOS Pathway Drives Malignancy in EGFRvIII-Activated Glioma Yeung, Caleb PI: Bonni, Azad
    • Functional Characterization of the NOD-like receptor NLRC3 in T Cell Activation Zhang, Chi PI: Kobayashi, Koichi
    • Lipid Composition Dependence and Hemifusion in Atlastin-Mediated Homotypic Membrane Fusion Zhou, Wenchi PI: Rapoport, Tom
    • Expression and Function of the Mammalian SID-1 Orthologs, SidT1 and SidT2 Song, Fei PI: Hunter, Craig
    • Characterizing the role of SERBP1 and Serpine1 in regulating Th1 cell-driven autoimmune disease Chen, Andrew PI: Kuchroo, Vijay
    • Mechanisms of Immune Control of Human Immunodeficiency Virus (HIV) in Absence of Protective HLA Class I Alleles Sierra-Davidson, Kailan PI: Walker, Bruce
    • Determining the Mechanism of Action of R7, A Small Molecule Inhibitor of the Anaphase-Promoting Complex/Cyclosome (APC/C) Zhao, Lillian PI: King, Randall
    • Embryonic Stem Cells Can Reconstitute the Epigenetic Landscape of H3K27me3 with High Fidelity after Global Erasure Mi, Xiaoli PI: Meissner, Alex
    • Spatial and Temporal Regulation of Genetic Diversity in Mycobacteria
      Ragheb, Mark PI: Fortune, Sarah
  • MCB Thesis 2011
    • The Hippo Pathway in Human Embryonic Stem Cells and Endodermal Progenitors Arledge, Walker (Cole) PI: Melton, Doug