Molecular mechanisms underlying viral genomic RNA – host interactions
Mechanisms of membrane-associated cell biological processes.
High resolution dynamic and spatial studies of prokaryotic cellular organization
Structural biology of signaling and transport through biological membranes
Molecular mechanisms of social behaviors, specifically self versus non-self recognition, in bacteria
Structure and function of membrane proteins
Development of chemical and molecular biology tools to allow new measurements and perturbations in biological systems; study mechanisms of gene regulation and dysregulation in cancer.
Development and application of chemical proteomic methods to study the interactions of therapeutics, natural products, and metabolites within the cellular proteome