Co-authors Andy McMahon (left) and Stephen Rodda The mammalian skeleton is important for many physiological functions; as a scaffold, it supports the body, enabling motion and mechanical loading,…
Tag: Publication
MAPPING EVOLUTION: LINKING ADAPTIVE TRAITS TO GENOMIC LOCATION
Authors Ayellet Segrè and Andrew Murray Life exists in an impressive variety of forms, but the processes responsible for generating all that variation typically take far longer than…
MAMMALIAN EGG PROGENITORS STAY PUT
Co-authors Amy Wagers and Kevin Eggan One of the central dogmas of mammalian reproduction is that females are born with a fixed pool of meiotic germ cells in…
NATURAL KILLERS HAVE A COMPLEX
Left to right: Xi Chen, Jack Strominger and Konrad Krzewski Natural killer (NK) cells comprise a relatively small subset of lymphocytes (~15%). Nonetheless, they play a very important…
TRANSLATING THE LANGUAGE OF PHEROMONES
When animals meet, how do they distinguish friend from foe? Such determinations must be made quickly, since any delay could mean a missed opportunity, but also accurately, since…
SPLITTING HEDGEHOG
Co-authors Tehyen Chu and Sam Kunes One of a cell’s fundamental tasks is to deliver its synthetic products to subcellular locations appropriate for their function. Nowhere is this…
CLUES TO SONIC HEDGEHOG’S BEHAVIOR
Co-authors Andy McMahon, Toyo Tenzen and Benjamin Allen The Hedgehog signaling pathway has emerged as a key regulator of normal embryonic development and a major contributor to a…
STAYING BALANCED AMONG THE CHATTERING CLASS
Imagine a cocktail party, full of conversing people. As a group, these people love to talk, but for a good party their chatter should be neither too quiet…
CORRELATED NEURAL ACTIVITY DICTATES CHANGES IN VISUAL INFORMATION PROCESSING
Young sensory systems often utilize stimuli present in the environment during development to refine information processing. These processes work to optimize the system for the encoding of future…
RUNNING THROUGH STOP SIGNS
First author of this paper, Antonia Holway One of the 10 biological commandments is "Thou shall keep thy genome stable!" One way that proliferating cells accomplish this is…
