100 years biochemical sciences tutorial
Bacillus subtilis is a bacterium with many talents. Some cells devote themselves to exploration, abandoning their relatives to live as swimming ‘motile’ cells. Others instead choose a cooperative,…
(l to r) Carl Wu, Vu Nguyen, Debbie Wei, Anand Ranjan, and Andres Leschziner Genome packaging is a universal process in eukaryotes. In the smallest repeating unit of…
A Zebrabow fish circled by a rainbow of ribosome profiles. In three papers published in Development, the Schier lab suggests that signals move through developing tissues by hindered…
(l to r) Howard Berg, Pushkar Lele, and Basarab Hosu Contact with a surface is believed to trigger bacterial swarmer-cell differentiation, and the flagellar motor is thought to…
Neurons send signals to other neurons along axons. Their growth is a major aspect of brain development, and one that occurs in a long series of steps. First,…
When we sniff an odor, it is first detected by a set of specific odorant receptors expressed by olfactory receptor neurons in the nose. Olfactory receptor neurons then…
(l to r) Takao K. Hensch, Henry H.C. Lee, and Alain Prochiantz A small group of highly metabolically active neurons act as conductors in the symphony that is…
In 2007, the labs of Professors Jeff Lichtman and Josh Sanes introduced a multicolor labeling strategy called “Brainbow.” It involves use of transgenic mice in which various combinations…
(l to r) Sophie de Buyl, Shu-Wen Teng, Jeffrey R. Moffitt, and Shankar Mukherji with Nikhil Living organisms tightly coordinate their physiology with the day and night cycle.…
(l to r) Guillaume Witz, Mara Prentiss, Nancy Kleckner, Beth Weiner, and Jay K. Fisher The E. coli chromosome is a single circular unit which, if stretched out,…
