John Koschwanez (l) and Andrew Murray How do microbes evolve to utilize nutrients that they can't import? We used engineering and experimental evolution of budding yeast to study…
Erin O'Shea (l) and Andrian Gutu The day-night cycle is the most predictable environmental variation on Earth. Many organisms, ranging from bacteria to humans have evolved endogenous time-keeping…
In recent years, a growing number of studies have reported the identity of genes that contribute to phenotypic variation. However, few have narrowed the causative effects down to…
What is the function of a sensory system? One straightforward idea is that it strives to create a complete and accurate internal representation of the external world, which…
(L to R) Sirui Zou, Bret Redwine, Andres Leschziner, Rogelio Hernandez-Lopez, and Samara Reck-Peterson, front row Locksley Walking takes an enormous amount of coordination. As your leading foot…
(L to R) Dimitar Kostadinov, Joshua Sanes, and Julie Lefebvre Neurons in the brain extend elaborately branched dendrites that receive inputs from other neurons and sensory stimuli. In…
Biological systems are inherently noisy: they contain randomness beyond an observer’s control. The most common approach to deal with noise is simply to throw it away: by…
Severe microbial infections, such as tuberculosis and MRSA, often require treatment with three (or more) drugs. Multidrug therapies are currently discovered by empirically testing large numbers of potentially…
You can't miss it in the news these days: neuroscientists are excited about anatomical reconstruction of neural connectivity. In fact, the term "connectomics" is a frequently-edited entry in…
The goal of this study was to investigate the pattern of nerve connections between motor neurons and muscle fibers in newborn and embryonic animals. Previous work by us…
