All cells contain a network of molecular chaperones that help other proteins (often called “clients”) fold into functional three-dimensional conformations. Decades of research on chaperones has led to…
Tag: Vlad Denic
Denic Lab Discovers an Ancient and Essential Translation Factor Chaperone
Billions of years ago, the first eukaryotic common ancestor split from its archaeal lineage with a distinct set of genes, the majority of which many of us (eukaryotes)…
Who is Watching the Watchman on Yeast Peroxisome? [Denic Lab]
In a new paper published in eLife, my colleagues in the Denic Lab and I investigated how budding yeast (S. cerevisiae) breaks down damaged peroxisome organelles through a…
Astellas-Harvard Research Alliance to Fund Collaboration Between Denic Lab and Harper Lab (HMS)
MCB faculty Vlad Denic has been chosen to receive funding for a joint project with HMS professor Wade Harper from a strategic research alliance between the pharmaceutical company…
How to Prepare the Next Generation for the Future by Eating Yourself [Denic Lab]
Gametes are the vessels of gene immortality. To escape the dying soma, these cells rely on a specialized form of the cell cycle in which a single round…
The Beginning of the End for Ricin Starts at the Tail [Denic Lab]
In the late 1970’s, the KGB inducted ricin into the “cloak and dagger” hall-of-fame by turning a more or less innocuous umbrella tip into their assassin’s weapon of…
Biology by Any Means Necessary: Vlad Denic in MCB
Sometimes how you get where you’re going is as important as what you do when you get there. This is true of the proteins in our cells, whose…
Controlling Organellar Excess: Msp1 Eliminates Undesired Membrane Proteins from Mitochondria and Peroxisomes [Denic Lab]
The phrase “finding a needle in a haystack” refers to the difficulty of locating a specific target among a large number of very similar objects. Living cells face…
TURNING UP THE HEAT ON PROTEIN FOLDING BY TURNING DOWN HEAT SHOCK FACTOR [DENIC LAB]
(l to r) David Pincus, Eric Solís, Vlad Denic No matter where you fall on the spectrum of libertarianism this election year, you can hopefully appreciate that the…
VLAD DENIC RECEIVES EARLY CAREER LIFE SCIENTIST AWARD
The American Society for Cell Biology (ASCB) recently selected Vlad Denic, a Professor in the Department of Molecular and Cellular Biology, as the recipient of this year’s Early…
