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Motile behavior of bacteria: sensory transduction in bacterial chemotaxis (in E. coli), dynamics of the flagellar rotary motor, propulsion of non-flagellated bacteria
Real-time systems analysis of signal transduction and genetic networks at the single cell level
High resolution dynamic and spatial studies of prokaryotic cellular organization
Quantitative studies of biological self-organization, and the architecture and dynamics of subcellular structures
Multicolor and time-resolved electron microscopy of cell signaling