Motile behavior of bacteria: sensory transduction in bacterial chemotaxis (in E. coli), dynamics of the flagellar rotary motor, propulsion of non-flagellated bacteria
Real-time systems analysis of signal transduction and genetic networks at the single cell level
Mechanisms of membrane-associated cell biological processes.
High resolution dynamic and spatial studies of prokaryotic cellular organization
Molecular mechanisms of social behaviors, specifically self versus non-self recognition, in bacteria
C. elegans genetics of intercellular RNAi signaling
Mechanisms of antibiotics and antibiotic resistance
Chromosomes: motion, mechanics, DNA dynamics and spatial patterning
Development of the nervous system, synaptic plasticity, behavior and evolution
Developmental plasticity, epigenetics and cell fate specification; environmental signaling in development (not taking students)
Chromosome segregation, yeast sex, and evolution
Quantitative studies of biological self-organization, and the architecture and dynamics of subcellular structures.
Developmental Genetics and Neurobiology (not taking students)
Biophysical studies with nanopores
Reversible phosphorylation and cell proliferation
Fundamental questions in cell signaling and homeostasis