News from 2019

NEW STRUCTURAL RNAS? NOW WE CAN TELL [RIVAS AND EDDY LABS]

Some fundamental cellular activities are directed by RNA-based machines. The RNAs in these machines adopt distinct three-dimensional structures in order to facilitate their function, much in the way…

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NEURAL CIRCUITS AT THE BRAIN SCALE [ENGERT LAB]

A longstanding goal of neuroscience is to figure out how the brain reacts to what is happening in the outside world. But it has been challenging to map…

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HOW A MAMMAL GOT ITS STRIPES [HOEKSTRA LAB]

by the astonishing variety of forms, shapes, and colors that have evolved in nature. This variation has allowed organisms to adapt to their local environments, for example, to…

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YIGONG SHI TO DELIVER JOHN T. EDSALL LECTURE

Yigong Shi is a University Professor at Tsinghua University, Beijing, China. He was born and raised in China and received his Bachelor’s Degree in Biology from Tsinghua University…

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FINDING FORKS IN THE ROAD OF HUMAN BRAIN DEVELOPMENT [RAMANATHAN LAB]

Human brain cells begin their lives as pluripotent cells with the potential to develop into any cell type in the body. As those pluripotent stem cells differentiate and…

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COMMON CURRENCY FOR REWARD AND PUNISHMENT [UCHIDA LAB]

Considering both good and bad is fundamental for future planning and decision-making. When animals forage, they may consider how tasty the food is, how much food is available…

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MOLECULAR COMPETITION ENHANCES SYNAPTIC SPECIFICITY [SANES LAB]

As neurons develop in the central nervous system, they encounter many potential synaptic partners, and choose among them to form stable connections with only a few. The specific…

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A NATURAL ANTICANCER COMPOUND DESTABILIZES THE CELL MEMBRANE BY REACTING WITH LIPIDS [O’SHEA LAB]

Many of the approved chemotherapy drugs are either collected from natural sources or inspired by molecules existing in nature. Natural products with anticancer activity can be readily identified…

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