Department News News Archive

News archive

Tag: Publication

The ‘Right’ Diet. Discovery of Entirely New Class of Enzymes Could One Day Lead to Bespoke Diets, Therapeutics

Everyone seems to have an opinion about which foods to eat or avoid, how to lose weight (and keep it off!), and which superfood to horde. But there’s…

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Parental Influence on Gene Regulation in the Brain [Whipple Lab]

Mammals inherit two copies of each gene—one from their mother and one from their father. In most cases, the gene copy inherited from each parent is functionally indistinguishable.…

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How to Prepare the Next Generation for the Future by Eating Yourself [Denic Lab]

Gametes are the vessels of gene immortality. To escape the dying soma, these cells rely on a specialized form of the cell cycle in which a single round…

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A Small but Important Difference [Sanes Lab]

Neurons come in a bewildering variety of shapes and sizes, with the structure of each type underlying its specific functions. A major preoccupation of developmental biologists is to…

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Foresight in Fish: Physical Intelligence during 3D Prey Capture [Engert Lab]

Babies possess the ability to predict what will happen in their environment based on intuition about gravity, motion, and mass of objects. This has lead to the idea…

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Larval Zebrafish As a Model for Perceptual Decision-making [Engert lab]

During perceptual decision-making, animals need to accumulate sensory evidence over time, but the underlying neural processes remain poorly understood. Here we combine behavioral experiments and whole-brain imaging in…

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Weathering the Storm of Axonal Injury [Sanes Lab]

Injury to the central nervous system (brain or spinal cord) usually leads to irreversible loss of function. This is because many injured neurons die and few if any…

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A Closer Look at Neuronal Rewiring in Brain Development [Lichtman Lab]

In many vertebrates, neural circuits undergo substantial reorganization in early postnatal life. This reorganization strengthens some neuron-to-neuron connections, while other neuronal connections are weakened by synapse elimination. It…

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The Beginning of the End for Ricin Starts at the Tail [Denic Lab]

In the late 1970’s, the KGB inducted ricin into the “cloak and dagger” hall-of-fame by turning a more or less innocuous umbrella tip into their assassin’s weapon of…

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A Homeostatic Circuit for Hunger [Engert and Kunes Labs]

Decades ago, pioneering studies in cats and rodents identified regions within an ancient part of the brain, the hypothalamus, that are sufficient to increase or reduce appetite. Stimulating…

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