73 publications listed for 2012:
- Budin, I, Debnath, A, and Szostak, JW. (2012) Concentration-driven growth of model protocell membranes. J. Am. Chem. Soc., 134(51):20812-9. PMID: 23198690PMC3530389
Jack Szostak Lab (HMS GENETICS)
- Guo, Y, Monahan, K, Wu, H, Gertz, J, Varley, KE, Li, W, Myers, RM, Maniatis, T, and Wu, Q. (2012) CTCF/cohesin-mediated DNA looping is required for protocadherin α promoter choice. Proc. Natl. Acad. Sci. U.S.A., 109(51):21081-6. PMID: 23204437PMC3529044
Tom Maniatis Lab (MCB)
- Peterson, KA, Nishi, Y, Ma, W, Vedenko, A, Shokri, L, Zhang, X, McFarlane, M, Baizabal, JM, Junker, JP, van Oudenaarden, A, Mikkelsen, T, Bernstein, BE, Bailey, TL, Bulyk, ML, Wong, WH, andMcMahon, AP. (2012) Neural-specific Sox2 input and differential Gli-binding affinity provide context and positional information in Shh-directed neural patterning. Genes Dev., 26(24):2802-16. PMID: 23249739PMC3533082
Andrew McMahon Lab (MCB)
- Ewen-Campen, B, Srouji, JR, Schwager, EE, and Extavour, CG. (2012) Oskar predates the evolution of germ plasm in insects. Curr. Biol., 22(23):2278-83. PMID:23122849
Cassandra Extavour Lab (OEB)
Andres Leschziner Lab (MCB)
- Green, DA, and Extavour, CG. (2012) Convergent evolution of a reproductive trait through distinct developmental mechanisms in Drosophila. Dev. Biol., 372(1):120-30. PMID: 23022298
Cassandra Extavour Lab (OEB)
- Didovyk, A, and Verdine, GL. (2012) Structural origins of DNA target selection and nucleobase extrusion by a DNA cytosine methyltransferase. J. Biol. Chem., 287(48):40099-105. PMID: 23012373PMC3504724
Gregory Verdine Lab (SCRB)
- Peacock-Villada, A, Yang, D, Danilowicz, C, Feinstein, E, Pollock, N, McShan, S, Coljee, V, and Prentiss, M. (2012) Complementary strand relocation may play vital roles in RecA-based homology recognition. Nucleic Acids Res., 40(20):10441-51. PMID: 22941658PMC3488227
Mara Prentiss Lab (PHYSICS)
- De la Huerta, I, Kim, IJ, Voinescu, PE, and Sanes, JR. (2012) Direction-selective retinal ganglion cells arise from molecularly specified multipotential progenitors. Proc. Natl. Acad. Sci. U.S.A., 109(43):17663-8. PMID: 23045641 PMC3491461
Joshua Sanes Lab (MCB)
- Zhuang, JJ, and Hunter, CP. (2012) The Influence of Competition Among C. elegans Small RNA Pathways on Development. Genes (Basel), 3(4). PMID: 23483754PMC3592204
Craig Hunter Lab (MCB)
- Zhang, X, and Zhang, Y. (2012) DBL-1, a TGF-β, is essential for Caenorhabditis elegans aversive olfactory learning. Proc. Natl. Acad. Sci. U.S.A., 109(42):17081-6. PMID: 23019581 PMC3479501
Yun Zhang Lab (OEB)
- Kocabas, A, Shen, CH, Guo, ZV, andRamanathan, S. (2012) Controlling interneuron activity in Caenorhabditis elegans to evoke chemotactic behaviour. Nature, 490(7419):273-7. PMID: 23000898
Sharad Ramanathan Lab (MCB)
- Nannas, NJ, and Murray, AW. (2012) Complications dawn for kinetochore regulation by Aurora. Proc. Natl. Acad. Sci. U.S.A., 109(40):15972-3. PMID: 22991465PMC3479548
Andrew Murray Lab (MCB)
- Gleason, EJ, and Kramer, EM. (2012) Characterization of Aquilegia Polycomb Repressive Complex 2 homologs reveals absence of imprinting. Gene, 507(1):54-60. PMID: 22796128
Elena Kramer Lab (OEB)
- Chand, NS, Clatworthy, AE, and Hung, DT. (2012) The two-component sensor KinB acts as a phosphatase to regulate Pseudomonas aeruginosa Virulence. J. Bacteriol., 194(23):6537-47. PMID:23024348 PMC3497526
Deborah Hung Lab (HMS MICROBIO)
- Datta, SS, Kim, SH, Paulose, J, Abbaspourrad, A, Nelson, DR, and Weitz, DA. (2012) Delayed buckling and guided folding of inhomogeneous capsules. Phys. Rev. Lett., 109(13):134302. PMID:23030092
David Weitz Lab (SEAS)
- McEwan, DL, Weisman, AS, and Hunter, CP. (2012) Uptake of extracellular double-stranded RNA by SID-2. Mol. Cell, 47(5):746-54. PMID: 22902558PMC3488460
Craig Hunter Lab (MCB)
- Gujral, TS, Karp, RL, Finski, A, Chan, M, Schwartz, PE, MacBeath, G, and Sorger, P. (2012) Profiling phospho-signaling networks in breast cancer using reverse-phase protein arrays. Oncogene, . PMID:22945653
Gavin MacBeath Lab (HMS SYSBIO)
- Carter-O’Connell, I, Peel, MT, Wykoff, DD, and O’Shea, EK. (2012) Genome-Wide Characterization of the Phosphate Starvation Response in Schizosaccharomyces pombe. BMC Genomics, 13:697. PMID: 23231582PMC3556104
Erin O’Shea Lab (MCB)
- Freudiger, CW, Pfannl, R, Orringer, DA, Saar, BG, Ji, M, Zeng, Q, Ottoboni, L, Wei, Y, Ying, W, Waeber, C, Sims, JR, De Jager, PL, Sagher, O, Philbert, MA, Xu, X, Kesari, S, Xie, XS, and Young, GS. (2012) Multicolored stain-free histopathology with coherent Raman imaging. Lab. Invest., 92(10):1492-502. PMID: 22906986PMC3622202
X. Sunney Xie Lab (CCB)
- Kao, RM, Vasilyev, A, Miyawaki, A, Drummond, IA, and McMahon, AP. (2012) Invasion of distal nephron precursors associates with tubular interconnection during nephrogenesis. J. Am. Soc. Nephrol., 23(10):1682-90. PMID: 22904347PMC3458467
Andrew McMahon Lab (MCB)
- Hsu, PD, and Zhang, F. (2012) Dissecting neural function using targeted genome engineering technologies. ACS Chem Neurosci, 3(8):603-10. PMID: 22896804PMC3419454
Xiaowei Zhuang Lab (CCB)
Feng Zhang Lab (BROAD)
- Lo, SM, McElroy, KA, and Francis, NJ. (2012) Chromatin modification by PSC occurs at one PSC per nucleosome and does not require the acidic patch of histone H2A. PLoS ONE, 7(10):e47162. PMID: 23071745PMC3469540
Nicole Francis Lab (MCB)
Mitzi Kuroda Lab (HMS GENETICS)
- Grant, SS, Kaufmann, BB, Chand, NS, Haseley, N, and Hung, DT. (2012) Eradication of bacterial persisters with antibiotic-generated hydroxyl radicals. Proc. Natl. Acad. Sci. U.S.A., 109(30):12147-52. PMID: 22778419 PMC3409745
Deborah Hung Lab (HMS MICROBIO)
- Bianco, IH, Ma, LH, Schoppik, D, Robson, DN, Orger, MB, Beck, JC, Li, JM, Schier, AF, Engert, F, and Baker, R. (2012) The tangential nucleus controls a gravito-inertial vestibulo-ocular reflex. Curr. Biol., 22(14):1285-95. PMID: 22704987
Alex Schier Lab (MCB)
- Crenshaw, CM, Nam, K, Oo, K, Kutchukian, PS, Bowman, BR, Karplus, M, and Verdine, GL. (2012) Enforced presentation of an extrahelical guanine to the lesion recognition pocket of human 8-oxoguanine glycosylase, hOGG1. J. Biol. Chem., 287(30):24916-28. PMID: 22511791PMC3408145
Gregory Verdine Lab (SCRB)
- Carrasquillo, R, Tian, D, Krishna, S,Pollak, MR, Greka, A, and Schlöndorff, J. (2012) SNF8, a member of the ESCRT-II complex, interacts with TRPC6 and enhances its channel activity. BMC Cell Biol., 13:33. PMID: 23171048 PMC3520717
Martin Pollak Lab (HMS BBS)
- Thuo, MM, Reus, WF, Simeone, FC, Kim, C, Schulz, MD, Yoon, HJ, and Whitesides, GM. (2012) Replacing -CH2CH2- with -CONH- does not significantly change rates of charge transport through Ag(TS)-SAM//Ga2O3/EGaIn junctions. J. Am. Chem. Soc., 134(26):10876-84. PMID:22676159
George Whitesides Lab (CCB)
- Lo, SM, Follmer, NE, Lengsfeld, BM, Madamba, EV, Seong, S, Grau, DJ, andFrancis, NJ. (2012) A bridging model for persistence of a polycomb group protein complex through DNA replication in vitro. Mol. Cell, 46(6):784-96. PMID: 22749399PMC3389374
Nicole Francis Lab (MCB)
- Reus, WF, Thuo, MM, Shapiro, ND, Nijhuis, CA, and Whitesides, GM. (2012) The SAM, not the electrodes, dominates charge transport in metal-monolayer//Ga2O3/gallium-indium eutectic junctions. ACS Nano, 6(6):4806-22. PMID: 22548354
George Whitesides Lab (CCB)
- Monahan, K, Rudnick, ND, Kehayova, PD, Pauli, F, Newberry, KM, Myers, RM, andManiatis, T. (2012) Role of CCCTC binding factor (CTCF) and cohesin in the generation of single-cell diversity of protocadherin-α gene expression. Proc. Natl. Acad. Sci. U.S.A., 109(23):9125-30. PMID: 22550178PMC3384188
Tom Maniatis Lab (MCB)
- Rosains, J, and Mango, SE. (2012) Genetic characterization of smg-8 mutants reveals no role in C. elegans nonsense mediated decay. PLoS ONE, 7(11):e49490. PMID:23166684 PMC3500306
Susan Mango Lab (MCB)
- Lazarus, MB, Jiang, J, Gloster, TM, Zandberg, WF, Whitworth, GE, Vocadlo, DJ, and Walker, S. (2012) Structural snapshots of the reaction coordinate for O-GlcNAc transferase. Nat. Chem. Biol., 8(12):966-8. PMID: 23103939PMC3508357
Suzanne Walker Lab (HMS SYSBIO)
Daniel Kahne Lab (CCB)
- Kim, YG, Lone, AM, Nolte, WM, andSaghatelian, A. (2012) Peptidomics approach to elucidate the proteolytic regulation of bioactive peptides. Proc. Natl. Acad. Sci. U.S.A., 109(22):8523-7. PMID:22586115 PMC3365226
Alan Saghatelian Lab (CCB)
- Cook, KE, and O’Shea, EK. (2012) Hog1 controls global reallocation of RNA Pol II upon osmotic shock in Saccharomyces cerevisiae. G3 (Bethesda), 2(9):1129-36. PMID: 22973550 PMC3429927
Erin O’Shea Lab (MCB)
- Hacisuleyman, E, Cabili, MN, and Rinn, JL. (2012) A Keystone for ncRNA. Genome Biol., 13(5):315. PMID: 22632630PMC3446285
John Rinn Lab (SCRB)
- Sung, RJ, Zhang, M, Qi, Y, and Verdine, GL. (2012) Sequence-dependent structural variation in DNA undergoing intrahelical inspection by the DNA glycosylase MutM. J. Biol. Chem., 287(22):18044-54. PMID:22465958 PMC3365742
Gregory Verdine Lab (SCRB)
- Gude, L, Berkovitch, SS, Santos, WL, Kutchukian, PS, Pawloski, AR, Kuimelis, R, McGall, G, and Verdine, GL. (2012) Mapping targetable sites on human telomerase RNA pseudoknot/template domain using 2′-OMe RNA-interacting polynucleotide (RIPtide) microarrays. J. Biol. Chem., 287(22):18843-53. PMID:22451672 PMC3365779
Gregory Verdine Lab (SCRB)
- Grama, A, and Engert, F. (2012) Direction selectivity in the larval zebrafish tectum is mediated by asymmetric inhibition. Front Neural Circuits, 6:59. PMID: 22969706PMC3432856
Florian Engert Lab (MCB)
- Ahrens, MB, Li, JM, Orger, MB, Robson, DN, Schier, AF, Engert, F, and Portugues, R. (2012) Brain-wide neuronal dynamics during motor adaptation in zebrafish. Nature, 485(7399):471-7. PMID: 22622571
Alex Schier Lab (MCB)
- Loy, RE, Lueck, JD, Mostajo-Radji, MA, Carrell, EM, and Dirksen, RT. (2012) Allele-specific gene silencing in two mouse models of autosomal dominant skeletal myopathy. PLoS ONE, 7(11):e49757. PMID: 23152933PMC3495761
Paola Arlotta Lab (SCRB)
- Müller, P, Rogers, KW, Jordan, BM, Lee, JS, Robson, D, Ramanathan, S, andSchier, AF. (2012) Differential diffusivity of Nodal and Lefty underlies a reaction-diffusion patterning system. Science, 336(6082):721-4. PMID: 22499809PMC3525670
Alex Schier Lab (MCB)
- Lee, MJ, Ye, AS, Gardino, AK, Heijink, AM, Sorger, PK, MacBeath, G, and Yaffe, MB. (2012) Sequential application of anticancer drugs enhances cell death by rewiring apoptotic signaling networks. Cell, 149(4):780-94. PMID: 22579283
Gavin MacBeath Lab (HMS SYSBIO)
- Mekhoubad, S, Bock, C, de Boer, AS, Kiskinis, E, Meissner, A, and Eggan, K. (2012) Erosion of dosage compensation impacts human iPSC disease modeling. Cell Stem Cell, 10(5):595-609. PMID: 22560080
Kevin Eggan Lab (SCRB)
- Moffitt, JR, Lee, JB, and Cluzel, P. (2012) The single-cell chemostat: an agarose-based, microfluidic device for high-throughput, single-cell studies of bacteria and bacterial communities. Lab Chip, 12(8):1487-94. PMID: 22395180
Sharad Ramanathan Lab (MCB)
- Vigneault, F, Ter-Ovanesyan, D, Alon, S, Eminaga, S, C Christodoulou, D, Seidman, JG, Eisenberg, E, and M Church, G. (2012) High-throughput multiplex sequencing of miRNA. Curr Protoc Hum Genet, Chapter 11:Unit 11.12.1-10. PMID: 22470142
George Church Lab (HMS GENETICS)
- Kubicek, S, Gilbert, JC, Fomina-Yadlin, D, Gitlin, AD, Yuan, Y, Wagner, FF, Holson, EB, Luo, T, Lewis, TA, Taylor, B, Gupta, S, Shamji, AF, Wagner, BK, Clemons, PA, andSchreiber, SL. (2012) Chromatin-targeting small molecules cause class-specific transcriptional changes in pancreatic endocrine cells. Proc. Natl. Acad. Sci. U.S.A., 109(14):5364-9. PMID: 22434908PMC3325696
Stuart Schreiber Lab (CCB)
- Banse, SA, and Hunter, CP. (2012) Vampiric isolation of extracellular fluid from Caenorhabditis elegans. J Vis Exp, (61). PMID: 22453516
Craig Hunter Lab (MCB)
- Kuballa, P, Nolte, WM, Castoreno, AB, and Xavier, RJ. (2012) Autophagy and the immune system. Annu. Rev. Immunol., 30:611-46. PMID: 22449030
Alan Saghatelian Lab (CCB)
- Sarikaya, DP, Belay, AA, Ahuja, A, Dorta, A,Green, DA, and Extavour, CG. (2012) The roles of cell size and cell number in determining ovariole number in Drosophila. Dev. Biol., 363(1):279-89. PMID: 22200592
Cassandra Extavour Lab (OEB)
- Fu, D, Lu, FK, Zhang, X, Freudiger, C, Pernik, DR, Holtom, G, and Xie, XS. (2012) Quantitative chemical imaging with multiplex stimulated Raman scattering microscopy. J. Am. Chem. Soc., 134(8):3623-6. PMID: 22316340PMC3396204
X. Sunney Xie Lab (CCB)
- Chang, TY, Pardo-Martin, C, Allalou, A, Wählby, C, and Yanik, MF. (2012) Fully automated cellular-resolution vertebrate screening platform with parallel animal processing. Lab Chip, 12(4):711-6. PMID:22159032 PMC3415711
Mehmet Fatih Yanik Lab (MIT-NEURO)
- Kolinski, JM, Rubinstein, SM, Mandre, S, Brenner, MP, Weitz, DA, and Mahadevan, L. (2012) Skating on a film of air: drops impacting on a surface. Phys. Rev. Lett., 108(7):074503. PMID: 22401209
L Mahadevan Lab (SEAS)
- Akopian, V, Chan, MM, Clement, K, Galonska, C, Gifford, CA, Lehtola, E, Liao, J, Samavarchi-Tehrani, P, Sindhu, C, Smith, ZD, Tsankov, AM, Webster, J, Zhang, Y, Ziller, MJ, and Meissner, A. (2012) Epigenomics and chromatin dynamics. Genome Biol., 13(2):313. PMID: 22364154PMC3334565
Alex Meissner Lab (SCRB)
- Song, E, de Bivort, B, Dan, C, and Kunes, S. (2012) Determinants of the Drosophila odorant receptor pattern. Dev. Cell, 22(2):363-76. PMID: 22340498
Sam Kunes Lab (MCB)
- Beyer, EM, and MacBeath, G. (2012) Cross-talk between receptor tyrosine kinase and tumor necrosis factor-α signaling networks regulates apoptosis but not proliferation. Mol. Cell Proteomics, 11(6):M111.013292. PMID: 22323825PMC3433887
Gavin MacBeath Lab (HMS SYSBIO)
- Lau, DT, and Murray, AW. (2012) Mad2 and Mad3 cooperate to arrest budding yeast in mitosis. Curr. Biol., 22(3):180-90. PMID:22209528 PMC3277655
Andrew Murray Lab (MCB)
- Qi, Y, Nam, K, Spong, MC, Banerjee, A,Sung, RJ, Zhang, M, Karplus, M, andVerdine, GL. (2012) Strandwise translocation of a DNA glycosylase on undamaged DNA. Proc. Natl. Acad. Sci. U.S.A., 109(4):1086-91. PMID: 22219368PMC3268267
Gregory Verdine Lab (SCRB)
- Verdine, GL, and Hilinski, GJ. (2012) Stapled peptides for intracellular drug targets. Meth. Enzymol., 503:3-33. PMID:22230563
Gregory Verdine Lab (SCRB)
- Dearborn, RE, Dai, Y, Reed, B, Karian, T,Gray, J, and Kunes, S. (2012) Reph, a regulator of Eph receptor expression in the Drosophila melanogaster optic lobe. PLoS ONE, 7(5):e37303. PMID: 22615969PMC3353934
Sam Kunes Lab (MCB)
- Hou, J, Cohen, A. E., Motion induced by asymmetric degradation of hydrogels, Soft Matter, 8, 4616-4624, 2012
Adam Cohen Lab (CCB)
- Datta, SS, Kim, S-H, Paulose, J, Abbaspourrad, A, Nelson, DR, Weitz, DA. (2012) How does a porous shell collapse? Delayed buckling and guided folding of inhomogeneous capsules. Physical Review Letters 109: 134302.
David Weitz Lab (SEAS)
- Fung, J, Perry, RW, Dimiduk, TG,Manoharan, VN. 2012. Imaging multiple colloidal particles by fitting electromagnetic scattering solutions to digital holograms J Quant Spectroscopy Rad Transfer 113(18): 212-9.
Vinothan Manoharan Lab (SEAS)
- Jepsen, RA, Roberts, JD, Kearney, SP,Dimiduk, TG, O’Hern, TJ, Gailani, JZ. 2012. Shear Stress Measurements and Erosion Implications for Wave and Combined Wave-Current Generated Flows. J Wateray Port Coastal Ocean Engin-ASCE 138(4): 323-9.
Vinothan Manoharan Lab (SEAS)
- Perry, RW, Meng, G, Dimiduk, TG, Fung, J, Manoharan, VN. 2012. Real-space studies of the structure and dynamics of self-assembled colloidal clusters. Faraday Discussions 159: 211-234.
Vinothan Manoharan Lab (SEAS)
- Ferreira, LM, Floriddia, EM, Quadrato, G, and Di Giovanni, S. (2012) Neural regeneration: lessons from regenerating and non-regenerating systems. Mol. Neurobiol., 46(2):227-41. PMID: 22717989
Chad Cowan Lab (SCRB)
Jack Strominger Lab (MCB)
- Walpita, D, Hasaka, T, Spoonamore, J, Vetere, A, Takane, KK, Fomina-Yadlin, D, Fiaschi-Taesch, N, Shamji, A, Clemons, PA, Stewart, AF, Schreiber, SL, and Wagner, BK. (2012) A human islet cell culture system for high-throughput screening. J Biomol Screen, 17(4):509-18. PMID: 22156222
Stuart Schreiber Lab (CCB)
- Zhuang, JJ, and Hunter, CP. (2012) RNA interference in Caenorhabditis elegans: uptake, mechanism, and regulation. Parasitology, 139(5):560-73. PMID:22075748
Craig Hunter Lab (MCB)
- Zhang, X, Roeffaers, MB, Basu, S, Daniele, JR, Fu, D, Freudiger, CW, Holtom, GR, and Xie, XS. (2012) Label-free live-cell imaging of nucleic acids using stimulated Raman scattering microscopy. Chemphyschem, 13(4):1054-9. PMID:22368112 PMC3516876
Tom Maniatis Lab (MCB)
X. Sunney Xie Lab (CCB)
- Pakotiprapha, D, Samuels, M, Shen, K, Hu, JH, and Jeruzalmi, D. (2012) Structure and mechanism of the UvrA-UvrB DNA damage sensor. Nat. Struct. Mol. Biol., 19(3):291-8. PMID: 22307053
David Jeruzalmi Lab (MCB)
- Georghiou, G, Kleiner, RE, Pulkoski-Gross, M, Liu, DR, and Seeliger, MA. (2012) Highly specific, bisubstrate-competitive Src inhibitors from DNA-templated macrocycles. Nat. Chem. Biol., 8(4):366-74. PMID: 22344177 PMC3307835
David Liu Lab (CCB)
- Jabaudon, D, Shnider, SJ, Tischfield, DJ, Galazo, MJ, and Macklis, JD. (2012) RORβ induces barrel-like neuronal clusters in the developing neocortex. Cereb. Cortex, 22(5):996-1006. PMID: 21799210PMC3328343
Jeffrey Macklis Lab (SCRB)
- Fomina-Yadlin, D, Kubicek, S, Vetere, A, He, KH, He, KH, Schreiber, SL, and Wagner, BK. (2012) GW8510 increases insulin expression in pancreatic alpha cells through activation of p53 transcriptional activity. PLoS ONE, 7(1):e28808. PMID:22242153 PMC3252286
Stuart Schreiber Lab (CCB)
- Jiang, J, Lazarus, MB, Pasquina, L, Sliz, P, and Walker, S. (2012) A neutral diphosphate mimic crosslinks the active site of human O-GlcNAc transferase. Nat. Chem. Biol., 8(1):72-7. PMID: 22082911PMC3241908
Suzanne Walker Lab (HMS SYSBIO)
Daniel Kahne Lab (CCB)