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News from 2015

THE INPUTOME OF DOPAMINE NEURONS IDENTIFIED [UCHIDA LAB]

A central goal in neuroscience is to understand how diverse types of neurons interact to form complex networks. A critical step toward this goal is to find out…

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STUDY SUGGESTS NEURAL WIRING PEAKS AT BIRTH AND THEN IT’S ALL DOWNHILL FROM THERE [LICHTMAN LAB]

The goal of this study was to investigate the pattern of nerve connections between motor neurons and muscle fibers in newborn and embryonic animals. Previous work by us…

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SCULPTING SOUND SPACE IN THE DEVELOPING BRAIN

Brain functions, such as language, are shaped by experience during windows of heightened plasticity in early life. For example, children raised in an English- speaking environment will easily…

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RESOLVING THE MOLECULAR ARCHITECTURE OF SYNAPSES USING LIGHT MICROSCOPY

Synapses are highly specialized junctions between neurons that are the basis of our understanding of neuronal signal transmission and how memories are formed in the brain. The structure,…

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SNIFFING OUT THE ODOR CODE: A ROLE FOR SPIKE TIMING

How would you describe the smell of fresh baked bread, a rose, or an ocean breeze? The world of smell is extremely diverse, and with intangible qualities that…

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MICE THAT SMELL LIGHT

Olfaction is a critical sense for many animals, guiding their foraging behavior, mate choice and predator avoidance. Mice use ~1000 odorant receptor types in the main olfactory system…

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MOLECULAR MECHANICS OF HEARING AND DEAFNESS

Cadherin-23 stretching simulations. A close-up view of the linker region between cadherin-23 repeats 1 and 2 is shown during a molecular dynamics simulation in which the protein is…

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SEROTONIN AND SMELL

A moment’s introspection reveals that our perceptions and actions are strongly affected by our behavioral states.  Whether you are sleepy, awake, distracted or vigilant will affect how you…

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VISUAL SPACE WITHIN A DENDRITE

More than a century ago, famous neuroanatomist and histologist Ramon y Cajal proposed the idea that a neuron receives information through its extensive dendritic tree and sends it…

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