100 years biochemical sciences tutorial
Erin O'Shea, and Harold Kim One of the main challenges in the postgenomic era is to understand how genetic information is translated into quantitative transcriptional output. Transcription factors…
Co-authors (left to right): Hongkai Ji, Steven Vokes, Andrew McMahon and Wing H. Wong The vertebrate limb has been one of the central models for understanding the problem…
Many regions of the brain are organized in such a way that they form an ordered representation of our sensory experiences. Similar physical stimuli –nearby points of light…
(left panel) Monocular retinal innervation in a normal larval zebrafish. The right optic tectal lobe receives input solely from the contralateral (red) retina. (right panel) Following rewiring, the…
(L to R) Sayaka Sugiyama and Takao Hensch Researchers have long sought a factor that can trigger the brain’s ability to learn – and perhaps recapture the “sponge-like”…
(L to R) Andy McMahon, Todd Valerius, Josh Mugford, and Akio Kobayashi The kidney is a remarkable organ. Its actions maintain an appropriate water/salt balance within tissue fluids,…
The co-authors (left to right): M. Prentiss, R. Koszul, K.P. Kim, S. Kameoka, and N. Kleckner Movement plays important fundamental roles in basic chromosomal processes. Motion is most…
Some of the authors (left to right): Corey M McCann, Juan Carlos Tapia, and Jeff W Lichtman Image shows submandibular ganglion neurons (blue) that express Cyan Fluorescent Protein…
The human brain represents approximately 2% of the total body weight, but accounts for about 20% of the energy consumed. Functional hyperemia (local increases in blood flow triggered…
Erin O'Shea, and Felix Lam If stretched end-to-end, the DNA inside a single human cell would measure approximately 2-3 meters. A fiber of this length is physically compacted…
