Erin K. O'Shea and Xu Zhou Gene expression is controlled by a class of proteins called transcription factors. These proteins usually bind to short 6-8 base pair DNA…
A fundamental question in developmental biology is how multi-potent cells choose a fate. While we know a lot about how cell states are maintained through growing amounts of…
Michael J. Rust and Erin K. O'Shea Circadian clocks are biological oscillators that help organisms keep track of the time of the day and coordinate their behavior with…
"With the enormous advances made in the miniaturization of instruments, it is not unthinkable anymore that neuroethologists will, at one point in the future, be able to obtain…
Heungwon Park Over the last decade, there has been a series of remarkable studies dealing with the characterization of noise in gene regulatory networks and signaling pathways. However,…
Rich Losick Professors at large research universities have two important responsibilities: generating new knowledge and educating students. Sometimes these missions are seen as being in competition. Indeed, we…
Synapses are highly specialized junctions between neurons that are the basis of our understanding of neuronal signal transmission and how memories are formed in the brain. The structure,…
(L to R) Hirofumi Morishita and Takao K. Hensch Much of our behavior reflects the neural circuits sculpted by experience during early developmental critical periods. Such heightened brain…
Meiosis is a modified cellular program by which a single diploid cell gives rise to haploid gametes (e.g. sperm and egg). To this end, DNA replication is followed…
How would you describe the smell of fresh baked bread, a rose, or an ocean breeze? The world of smell is extremely diverse, and with intangible qualities that…
