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Mechanisms of parasitic behavior manipulation across molecules, cells and circuits.
High resolution dynamic and spatial studies of prokaryotic cellular organization
Development of chemical and molecular biology tools to allow new measurements and perturbations in biological systems; study mechanisms of gene regulation and dysregulation in cancer.
Immunology, microbiome, and diet.
Multicolor and time-resolved electron microscopy of cell signaling
Development and application of chemical proteomic methods to study the interactions of therapeutics, natural products, and metabolites within the cellular proteome
Computational methods to identify functional genomic sequences and structures. Quest for conserved RNA structures